Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012331 | 0.86 | HTT (0.58) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL8070122 | 0.84 | HTT (0.47) | SLC9A1HTTMAPTNPSR1PDE7A | |
| SCHEMBL8611539 | 0.84 | SLC9A1 (0.64) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL6816581 | 0.82 | CXCR2 (0.63) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL6354726 | 0.82 | SLC9A1 (0.59) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL2972082 | 0.80 | SLC9A1 (0.60) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL29386167 | 0.79 | SLC9A1 (0.63) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL10759973 | 0.79 | SLC9A1 (0.63) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL30296307 | 0.78 | SLC9A1 (0.55) | SLC9A1HTTCXCR2MAPTNPSR1 | |
| SCHEMBL8513944 | 0.77 | MAPT (0.55) | SLC9A1HTTCXCR2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0911317-A1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | L'OREAL (FR) | 1999-04-28 | — | — | EP | disclosed |