SCHEMBL808438

SCHEMBL808438

CCCCCP(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.38
SIGMAR1 Q99720 1/20 0.38
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
DNM1 Q05193 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 1/20 0.37
PCSK9 Q8NBP7 1/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
EPHX2 P34913 1/20 0.36
PKM P14618 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647076 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL108820 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL10871891 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL9414060 0.98 LTA4H (0.37) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL1726443 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL107883 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL4416335 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL49938 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL6291641 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1
SCHEMBL28829104 0.98 DNM1 (0.40) LTA4HSIGMAR1CES2CES1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 703 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184649-A Synthesis method of indolo [2,1-a ] isoquinoline 新疆大学 2024-06-14 CN claimed
CN-117903132-A Asymmetric total synthesis method of alkaloid MARTINELLIC ACID 中国科学技术大学 2024-04-19 CN claimed
CN-117903200-A Manganese-based halide capable of emitting light by force, preparation method and application thereof 南方科技大学 2024-04-19 CN claimed
CN-117902990-A Preparation method of ilalastine intermediate (R) -6- (2-amino-4-methoxyphenyl) -5,6,7, 8-tetrahydronaphthalene-2-ol 海化生命(厦门)科技有限公司 2024-04-19 CN claimed
CN-117903150-A Synthesis method of alkenyl substituted polycyclic nitrogen heterocycle 中国科学技术大学 2024-04-19 CN claimed
CN-116063967-B Quantum dot fluorescent colloid, quantum dot On-chip white light LED and preparation method thereof 华南师范大学 2024-02-27 CN claimed
CN-117447464-A Method for producing optically active compound 首日生物制药公司 2024-01-26 CN claimed
CN-117417398-A Preparation method of ivermectin 河北美荷药业有限公司 2024-01-19 CN claimed
CN-117343093-A Synthesis method of iron-catalyzed non-activated gem difluoro-bialkylene compound double-silicon-based 山西天宏达安医药科技有限公司 2024-01-05 CN claimed
CN-117209375-A Preparation method of polysubstituted chiral adipic acid compound containing quaternary carbon center 四川大学 2023-12-12 CN claimed
CN-1972898-A Process for the preparation of enantiomerically enriched beta amino acid derivatives MERCK & CO INC (US) 2007-05-30 CN claimed
CN-1805924-A Method of forming a carbon-heteroatom bond RHONE POULENC CHIMIE (FR) 2006-07-19 CN claimed
EP-1622861-A1 METHOD OF FORMING A CARBON-HETEROATOM BOND RHODIA CHIMIE (FR) 2006-02-08 EP claimed
CN-1216064-C Process for preparing 6-o-alkenyl-substituted erythromycin derivatives ABBOTT LAB (US) 2005-08-24 CN claimed
WO-2004101496-A1 METHOD OF FORMING A CARBON-HETEROATOM BOND RHODIA CHIMIE (FR) 2004-11-25 WO claimed
CN-1379780-A Process for preparing 6-o-alkenyl-substituted erythromycin derivatives ABBOTT LAB (US) 2002-11-13 CN claimed
CN-1032351-C Process for selective preparation of alkenecarboxylic acid derivatives SHELL INT RESEARCH (NL) 1996-07-24 CN claimed
EP-0631571-A1 PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES. DU PONT (US) 1995-01-04 EP claimed
EP-0369864-B1 Process for producing aromatic amines SUMITOMO CHEMICAL CO (JP) 1994-03-09 EP claimed
CN-87107325-A Selective preparation of alkene carboxylic acid derivatives 1988-06-22 CN claimed