Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.32 |
| ▸ | NPY4R | P50391 | 3/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158519 | 0.79 | ALOX15 (0.37) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL434308 | 0.78 | MEN1 (0.48) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL433663 | 0.77 | MEN1 (0.47) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| Acetic Acid SCHEMBL10783904 | 0.76 | MEN1 (0.43) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL5089242 | 0.76 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL18601807 | 0.76 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL11418945 | 0.76 | MEN1 (0.46) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL22277155 | 0.76 | MEN1 (0.50) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL17525175 | 0.76 | MEN1 (0.46) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL8084631 | 0.76 | GRIA1 (0.34) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861231-B1 | L-N6-(1-IMINOETHYL)LYSINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASEINHIBITORS | SEARLE & CO (US) | 2000-11-08 | — | — | EP | claimed |
| EP-0861231-B1 | L-N6-(1-IMINOETHYL)LYSINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASEINHIBITORS | SEARLE & CO (US) | 2000-11-08 | — | — | EP | disclosed |