Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070475 | 0.86 | MAPT (0.39) | LMNAMAPTTLR7RAB9A | |
| SCHEMBL6981801 | 0.77 | LMNA (0.35) | ALDH1A1LMNAMAPTTLR7TDP1 | |
| SCHEMBL6982621 | 0.70 | MAPT (0.38) | LMNAMAPT | |
| SCHEMBL21905159 | 0.68 | KCNH2 (0.45) | ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL8506338 | 0.64 | NR1H2 (0.37) | ALDH1A1MAPTCRHR1 | |
| SCHEMBL31530718 | 0.64 | MAPT (0.55) | ALDH1A1LMNAMAPTTDP1CRHR1 | |
| SCHEMBL11735724 | 0.64 | MAPT (0.50) | ALDH1A1LMNAMAPTTDP1CRHR1 | |
| SCHEMBL30742823 | 0.61 | NPC1 (0.51) | ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL27918079 | 0.60 | LTA4H (0.38) | — | |
| SCHEMBL11675033 | 0.58 | LTA4H (0.50) | ALDH1A1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034168-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | Bayer Aktiengesellschaft (DE) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999021841-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-06 | — | — | WO | disclosed |