Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084532 | 0.77 | ALDH1A1 (0.39) | LMNAMAPTCRHR1TLR7ALDH1A1 | |
| SCHEMBL6981805 | 0.67 | ALDH1A1 (0.36) | TLR7ALDH1A1 | |
| SCHEMBL6982621 | 0.66 | MAPT (0.38) | LMNAMAPTPDE4APDE4BPDE4C | |
| SCHEMBL8506338 | 0.65 | NR1H2 (0.37) | MAPTCRHR1ALDH1A1 | |
| SCHEMBL8070475 | 0.63 | MAPT (0.39) | LMNAMAPTPDE4APDE4BPDE4C | |
| SCHEMBL31530718 | 0.62 | MAPT (0.55) | LMNAMAPTCRHR1ALDH1A1TDP1 | |
| SCHEMBL11735724 | 0.62 | MAPT (0.50) | LMNAMAPTCRHR1ALDH1A1TDP1 | |
| SCHEMBL26819191 | 0.61 | TDP1 (0.44) | CRHR1ALDH1A1TDP1 | |
| SCHEMBL11029993 | 0.60 | ALDH1A1 (0.43) | MAPTALDH1A1TDP1 | |
| SCHEMBL27346803 | 0.60 | PKM (0.44) | LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037882-B1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER CROPSCIENCE AG (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1037882-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER AG (DE) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029677-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-17 | — | — | WO | disclosed |