Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235201 | 0.90 | HTR6 (0.52) | HTR6 | |
| SCHEMBL7160298 | 0.84 | HTR6 (0.67) | HTR6KDM4ELMNA | |
| SCHEMBL6236246 | 0.80 | HTR6 (0.53) | HTR6 | |
| SCHEMBL6234522 | 0.79 | HTR6 (0.52) | HTR6 | |
| SCHEMBL31588161 | 0.77 | HTR6 (0.71) | HTR6 | |
| SCHEMBL6234497 | 0.76 | TSHR (0.65) | HTR6 | |
| SCHEMBL6236033 | 0.76 | HTR6 (0.52) | HTR6 | |
| SCHEMBL7162815 | 0.74 | HTR6 (0.61) | HTR6 | |
| SCHEMBL7160310 | 0.73 | HTR6 (0.69) | HTR6 | |
| SCHEMBL32672558 | 0.72 | HTR6 (0.58) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049679-A2 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-08 | — | — | EP | claimed |
| WO-1999037623-A2 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | claimed |