Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236246 | 0.86 | HTR6 (0.53) | HTR6 | |
| SCHEMBL6234522 | 0.85 | HTR6 (0.52) | HTR6 | |
| SCHEMBL6188876 | 0.84 | HTR6 (0.58) | HTR6 | |
| SCHEMBL6235201 | 0.84 | HTR6 (0.52) | HTR6 | |
| SCHEMBL6234497 | 0.83 | TSHR (0.65) | HTR6 | |
| SCHEMBL32672558 | 0.79 | HTR6 (0.58) | HTR6 | |
| SCHEMBL32672532 | 0.77 | HTR6 (0.59) | HTR6 | |
| SCHEMBL4659557 | 0.77 | HTR6 (0.62) | HTR6 | |
| SCHEMBL6234462 | 0.76 | PDE4A (0.62) | HTR6 | |
| SCHEMBL6235673 | 0.76 | PDE4A (0.62) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049679-B1 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | claimed |
| US-6548504-B1 | Compounds | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-04-15 | — | — | US | claimed |
| EP-1049679-A2 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-08 | — | — | EP | claimed |
| WO-1999037623-A2 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | claimed |
| EP-1049679-B1 | SULPHONAMIDE DERIVATIVES FOR TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | disclosed |
| US-6548504-B1 | Compounds | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-04-15 | — | — | US | disclosed |