Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090591 | 0.91 | F10 (0.33) | F10SLC9A1 | |
| SCHEMBL8077107 | 0.90 | F10 (0.39) | F10SLC9A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8076894 | 0.87 | KMT2A (0.36) | F10KDM4EALDH1A1 | |
| SCHEMBL8088434 | 0.87 | S100A4 (0.37) | F10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9732430 | 0.86 | F10 (0.32) | F10 | |
| SCHEMBL8088427 | 0.86 | MAPT (0.33) | SLC9A1KDM4EALDH1A1 | |
| SCHEMBL8084217 | 0.84 | ALOX5 (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10521128 | 0.83 | KDM4E (0.36) | F10KDM4EALDH1A1 | |
| SCHEMBL8090664 | 0.82 | MAPT (0.46) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8077274 | 0.81 | F10 (0.39) | F10SLC9A1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0340718-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1989-11-08 | — | — | EP | disclosed |