Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084622 | 0.91 | F10 (0.33) | F10SLC9A1 | |
| SCHEMBL8077274 | 0.90 | F10 (0.39) | F10SLC9A1 | |
| SCHEMBL8077107 | 0.81 | F10 (0.39) | F10SLC9A1 | |
| SCHEMBL8085208 | 0.79 | F10 (0.33) | F10 | |
| SCHEMBL8085042 | 0.79 | RXFP1 (0.31) | — | |
| SCHEMBL9732430 | 0.78 | F10 (0.32) | F10 | |
| SCHEMBL8088434 | 0.78 | S100A4 (0.37) | F10 | |
| SCHEMBL8085327 | 0.78 | MAOB (0.37) | F10 | |
| SCHEMBL8076894 | 0.78 | KMT2A (0.36) | F10 | |
| SCHEMBL8088427 | 0.77 | MAPT (0.33) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0340718-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1989-11-08 | — | — | EP | disclosed |