Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 3/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 3/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149673 | 1.00 | TXNRD1 (0.40) | TXNRD1TXNRD3TXNRD2SLC5A2ALDH1A1 | |
| SCHEMBL29306309 | 1.00 | TXNRD1 (0.40) | TXNRD1TXNRD3TXNRD2SLC5A2ALDH1A1 | |
| SCHEMBL7154382 | 0.90 | SLC5A2 (0.41) | TXNRD1TXNRD3TXNRD2SLC5A2ALDH1A1 | |
| SCHEMBL31135220 | 0.90 | SLC5A2 (0.41) | TXNRD1TXNRD3TXNRD2SLC5A2ALDH1A1 | |
| SCHEMBL23252921 | 0.86 | TXNRD1 (0.42) | TXNRD1TXNRD3TXNRD2SLC5A2ALDH1A1 | |
| SCHEMBL23252821 | 0.84 | HPGD (0.34) | TXNRD1TXNRD3TXNRD2ALDH1A1TSHR | |
| SCHEMBL23252864 | 0.84 | ALDH1A1 (0.35) | TXNRD1TXNRD3TXNRD2ALDH1A1TSHR | |
| SCHEMBL7150901 | 0.82 | ALDH1A1 (0.44) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL31571169 | 0.82 | ALDH1A1 (0.44) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL19987642 | 0.82 | ALDH1A1 (0.44) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007653-A1 | CHIRAL HYDRIDE COMPLEXES | ZEELAND CHEMICALS, INC. (US) | 1998-02-26 | — | — | WO | claimed |
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | ANDERSON DEVELOPMENT COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| US-6090950-A | Chiral hydride complexes | ZEELAND CHEMICALS, INC. (US) | 2000-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | BRS3, BRSK1, CA4 | TXNRD1 4858/4885TXNRD3 4453/4885TXNRD2 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.