SCHEMBL8084791

SCHEMBL8084791

COc1c(O)cc(C)cc1-c1cc(C)cc(O)c1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
PIM1 P11309 3/20 0.50
MAPT P10636 4/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
POLB P06746 2/20 0.48
APEX1 P27695 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 1/20 0.48
MPI P34949 1/20 0.48
RECQL P46063 1/20 0.48
ACHE P22303 2/20 0.46
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
SELE P16581 1/20 0.46
ELANE P08246 2/20 0.46
ALOX15 P16050 2/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
PTPN1 P18031 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19034740 0.90 ACHE (0.59) TDP1PIM1MAPTALDH1A1KDM4E
SCHEMBL68928 0.87 TDP1 (0.67) TDP1PIM1MAPTALDH1A1KDM4E
SCHEMBL658125 0.81 PTPN1 (0.53) TDP1PIM1MAPTALDH1A1KDM4E
SCHEMBL31090180 0.81 PTPN1 (0.53) TDP1PIM1MAPTALDH1A1KDM4E
SCHEMBL1427958 0.79 ACHE (0.70) TDP1MAPTALDH1A1KDM4EPOLB
SCHEMBL29421895 0.79 ACHE (0.70) TDP1MAPTALDH1A1KDM4EPOLB
SCHEMBL11974268 0.74 LMNA (0.48) TDP1PIM1MAPTALDH1A1KDM4E
SCHEMBL17655758 0.73 ACHE (0.76) MAPTALDH1A1KMT2AACHECYP3A4
SCHEMBL16091526 0.73 ACHE (0.59) PIM1MAPTALDH1A1KDM4EPOLB
SCHEMBL28064053 0.73 ERN1 (0.58) TDP1PIM1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000143446-A MAKEUP COSMETIC KANEBO LTD 2000-05-23 JP disclosed