SCHEMBL808491

SCHEMBL808491

CN(C)c1cc(Cc2ccc(C(=O)O)c(N(C)C)c2)ccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.52
CTSB P07858 1/20 0.52
MMP9 P14780 1/20 0.52
DNMT1 P26358 1/20 0.52
DNMT3B Q9UBC3 1/20 0.52
DNMT3L Q9UJW3 1/20 0.52
DNMT3A Q9Y6K1 1/20 0.52
ALDH1A1 P00352 4/20 0.50
CDC25B P30305 1/20 0.50
CASP6 P55212 1/20 0.50
RCE1 Q9Y256 1/20 0.50
CFD P00746 1/20 0.47
HNF4A P41235 1/20 0.46
KDM4E B2RXH2 3/20 0.43
PKM P14618 1/20 0.43
PPARA Q07869 2/20 0.42
PPARG P37231 1/20 0.42
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
LTC4S Q16873 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200735 0.87 ALDH1A1 (0.46) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL23723105 0.82 PPARA (0.61) ALDH1A1KDM4EPKMPPARAPPARG
SCHEMBL2418032 0.80 GRIN2D (0.43) ALDH1A1KDM4EPPARAPPARGKAT8
SCHEMBL28374619 0.78 KDM4E (0.50) ALDH1A1HNF4AKDM4EMPOHDAC1
SCHEMBL343186 0.77 ALDH1A1 (0.73) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29424153 0.77 ALDH1A1 (0.73) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL2420457 0.77 CSNK2A1 (0.52) ALDH1A1TSHRGAAMAPT
SCHEMBL642243 0.77 HCAR3 (0.53) ALDH1A1KDM4EGLATSHRGAA
SCHEMBL29365057 0.76 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL21621 0.76 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007195-B1 POLYURETHANE SPRAY COMPOSITION CONTAINING A LACTONE VISCOSITY MODIFIER AND METHOD OF MAKING A CURED POLYURETHANE ARTICLE THEREFROM UNIROYAL, INC. (US) 1983-10-05 EP claimed
US-4234445-A CURING AGENT UNIROYAL, INC. (US) 1980-11-18 US claimed
US-20250041997-A1 NONWOVEN ABRASIVE ARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2025-02-06 US disclosed
EP-4433261-A1 NONWOVEN ABRASIVE ARTICLES AND METHODS OF MAKING THE SAME 3M Innovative Properties Company (US) 2024-09-25 EP disclosed
WO-2023084362-A1 NONWOVEN ABRASIVE ARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-05-19 WO disclosed
US-20210308834-A1 SELF-CONTAINED BUFFING ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2021-10-07 US disclosed
EP-3829816-A1 SELF-CONTAINED BUFFING ARTICLES 3M Innovative Properties Company (US) 2021-06-09 EP disclosed
EP-3105010-B1 ABRASIVE ARTICLE AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2021-04-28 EP disclosed
EP-3227053-B1 NONWOVEN ABRASIVE WHEEL WITH MOISTURE BARRIER LAYER 3M INNOVATIVE PROPERTIES CO (US) 2021-01-27 EP disclosed
US-20200230783-A1 NONWOVEN ABRASIVE WHEEL WITH MOISTURE BARRIER LAYER 3M INNOVATIVE PROPERTIES CO (US) 2020-07-23 US disclosed
US-20200180112-A1 CLEANING ARTICLE WITH DECORATIVE PARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2020-06-11 US disclosed
US-6979713-B2 Curable compositions and abrasive articles therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-27 US disclosed
EP-1565529-A1 CURABLE EMULSIONS AND ABRASIVE ARTICLES THEREFROM 3M Innovative Properties Company (US) 2005-08-24 EP disclosed
WO-2004048473-A1 CURABLE EMULSIONS AND ABRASIVE ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-06-10 WO disclosed
WO-2004048433-A1 CURABLE COMPOSITIONS AND ABRASIVE ARTICLES THEREFROM__________ 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-06-10 WO disclosed
US-20040101680-A1 CURABLE COMPOSITIONS AND ABRASIVE ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2004-05-27 US disclosed
US-20040102574-A1 Curable emulsions and abrasive articles therefrom 3M INNOVATIVE PROPERTIES COMPANY 2004-05-27 US disclosed
EP-0049985-A1 Polyurethane spray composition, a method of making a cured polyurethane article therefrom, and a cured polyurethane UNIROYAL, INC. (US) 1982-04-21 EP disclosed
US-4234445-A CURING AGENT UNIROYAL, INC. (US) 1980-11-18 US disclosed
US-4195148-A AND CURING AGENT; WEAR RESISTANT COATINGS UNIROYAL, INC. (US) 1980-03-25 US disclosed