SCHEMBL642243

SCHEMBL642243

CN(C)c1cc(C(=O)O)ccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.53
MYC P01106 1/20 0.47
KDM4E B2RXH2 4/20 0.47
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
TPMT P51580 1/20 0.46
ACE2 Q9BYF1 2/20 0.45
ALDH1A1 P00352 1/20 0.45
GLA P06280 1/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 2/20 0.43
HTT P42858 2/20 0.43
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6645180 0.89 AKR1C3 (0.49) HCAR3KDM4EALDH1A1GLAGAA
SCHEMBL8646661 0.84 HCAR3 (0.57) HCAR3MYCKDM4ECA1CA2
SCHEMBL31455673 0.84 KDM4E (0.47) HCAR3KDM4ECA1CA2CA12
SCHEMBL1730549 0.84 KDM4E (0.47) HCAR3KDM4ECA1CA2CA12
SCHEMBL13191913 0.82 KDM4E (0.48) HCAR3MYCKDM4ECA1CA2
SCHEMBL6646574 0.80 KMT2A (0.43) HCAR3MYCKDM4ECA1CA2
SCHEMBL29771091 0.80 HRH3 (0.48) HCAR3KDM4ECA1CA2CA12
SCHEMBL5322452 0.80 MAPT (0.57) HCAR3MYCKDM4ECA1CA2
SCHEMBL2420457 0.80 CSNK2A1 (0.52) CA1CA2CA12CA4CA6
SCHEMBL8699242 0.80 HCAR3 (0.53) HCAR3MYCKDM4ECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108978226-B Preparation and application method of polyurethane modified acrylate water repellent agent 江南大学 2020-01-17 CN claimed
EP-2348835-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS KNC NER Acquisition Sub, Inc. (US) 2011-08-03 EP claimed
WO-2010037045-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-04-01 WO claimed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-4505993-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE Kuraray Noritake Dental Inc. (JP) 2025-02-12 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-11786890-B2 Photo-redox titanium containing organic frameworks and methods of making and use thereof FLORIDA STATE UNIVERSITY (US) 2023-10-17 US disclosed
US-11786890-B2 Photo-redox titanium containing organic frameworks and methods of making and use thereof FLORIDA STATE UNIVERSITY (US) 2023-10-17 US disclosed
CN-101864193-A Pigment and manufacture method thereof, pigment dispersion and Yellow toner CANON KK 2010-10-20 CN disclosed
US-20100113828-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-05-06 US disclosed
WO-2010037045-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-04-01 WO disclosed
CN-101331193-A Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2008-12-24 CN disclosed
WO-1995005403-A1 RADIATION CURABLE ALK-1-ENYL ETHER POLYESTER PREPOLYMERS ISP INVESTMENTS INC. (US) 1995-02-23 WO disclosed
US-5342860-A Unsaturated polyesters based on a alkenyloxy-substituted glycol and having alkenyloxy-substituted alcohol end groups; protective coatings; rapid cure at room temperature ISP INVESTMENTS INC. (US) 1994-08-30 US disclosed
US-4198350-A Amination/demethylation process STANDARD OIL COMPANY (INDIANA) (US) 1980-04-15 US disclosed
US-4118439-A IONICALLY CROSSLINKED QUATERNARY AMMONIUM POLYMER RHONE-POULENC S.A. (FR) 1978-10-03 US disclosed
US-3953420-A Azo pigments derived from 2-hydroxy-3-carboxynaphthalene containing a substituted or unsubstituted phthalimide BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113828-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS COMT, HAAO, PNMT HCAR3 312/4885MYC 1292/4885KDM4E 357/4885
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE CDH1, MACF1, ICAM1 HCAR3 2285/4885MYC 2391/4885KDM4E 3559/4885
US-11786890-B2 Photo-redox titanium containing organic frameworks and methods of making and use thereof PPOX, PPIF, CYBB HCAR3 4531/4885MYC 1232/4885KDM4E 2531/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 HCAR3 822/4885MYC 3495/4885KDM4E 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.