Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085937 | 0.87 | CNR2 (0.43) | CNR2KMT2ANPC1ABCB1ABCC1 | |
| SCHEMBL23315583 | 0.78 | NPC1 (0.62) | KMT2ANPC1ABCB1ABCC1ACACB | |
| SCHEMBL5452259 | 0.72 | MAPT (0.46) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL4416570 | 0.72 | CNR2 (0.58) | CNR2 | |
| SCHEMBL11389038 | 0.71 | KMT2A (0.67) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL5452545 | 0.71 | MAPT (0.46) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL4418089 | 0.70 | CNR2 (0.82) | CNR2KMT2AABCB1MAPTHTT | |
| SCHEMBL6968803 | 0.70 | KMT2A (0.58) | KMT2ANPC1ABCB1ABCC1SMN1; SMN2 | |
| SCHEMBL4414117 | 0.69 | CNR2 (0.55) | CNR2KMT2ANPC1ABCB1SMN1; SMN2 | |
| SCHEMBL5132181 | 0.69 | AGTR2 (0.68) | KMT2ANPC1ACACBPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |