Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084275 | 0.84 | RXFP1 (0.31) | ALDH1A1 | |
| SCHEMBL8085086 | 0.82 | MALT1 (0.35) | MAPTKDM4E | |
| SCHEMBL8077225 | 0.82 | HSD17B1 (0.35) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8084362 | 0.81 | KDM4E (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8088427 | 0.81 | MAPT (0.33) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8084285 | 0.80 | RAB9A (0.39) | MAPTKDM4EALDH1A1 | |
| SCHEMBL10697804 | 0.79 | MAPT (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8084221 | 0.78 | — | — | |
| SCHEMBL9733351 | 0.75 | RXFP1 (0.31) | ALDH1A1 | |
| SCHEMBL8085042 | 0.75 | RXFP1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0340718-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1989-11-08 | — | — | EP | disclosed |