SCHEMBL9733351

SCHEMBL9733351

CC1(C)Oc2ccc(C=O)cc2C(n2ccccc2=O)=C1C=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084275 0.88 RXFP1 (0.31) RXFP1ALDH1A1
SCHEMBL9733388 0.87 NR1H4 (0.32)
SCHEMBL9734444 0.84 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9733395 0.84 S100A4 (0.35)
SCHEMBL9368399 0.84 ABCC9 (0.34)
SCHEMBL9737114 0.84 F10 (0.38) ALDH1A1
SCHEMBL9732430 0.83 F10 (0.32)
SCHEMBL9732982 0.82 ALOX5 (0.38) ALDH1A1
SCHEMBL8085042 0.79 RXFP1 (0.31) RXFP1ALDH1A1
SCHEMBL7266931 0.78 RXFP1 (0.32) RXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5143924-A OXODIHYDROPYRIDYL CHROMAN DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-09-01 US disclosed