SCHEMBL8085263

SCHEMBL8085263

Oc1ccc[n+](Cc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
NPSR1 Q6W5P4 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KDM4E B2RXH2 2/20 0.53
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
ACHE P22303 3/20 0.44
ALDH1A1 P00352 3/20 0.43
CHKA P35790 3/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
RAB9A P51151 1/20 0.41
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL2453932 0.98 LMNA (0.59) LMNANPSR1L3MBTL1KDM4ECYP1A2
Bromide SCHEMBL6981181 0.98 LMNA (0.59) LMNANPSR1L3MBTL1KDM4ECYP1A2
Hydrochloric Acid SCHEMBL3196752 0.98 LMNA (0.65) LMNANPSR1L3MBTL1KDM4ECYP1A2
Hydrochloric Acid SCHEMBL31272185 0.98 LMNA (0.65) LMNANPSR1L3MBTL1KDM4ECYP1A2
Bromide SCHEMBL31255661 0.98 LMNA (0.59) LMNANPSR1L3MBTL1KDM4ECYP1A2
SCHEMBL2737208 0.79 LMNA (0.92) LMNANPSR1L3MBTL1KDM4ECYP1A2
SCHEMBL28842894 0.79 CALM1 (0.45) LMNAL3MBTL1KDM4EHTT
Hydrochloric Acid SCHEMBL23611562 0.78 CALM1 (0.44) LMNAL3MBTL1KDM4EHTT
SCHEMBL13933997 0.77 LMNA (0.58) LMNANPSR1L3MBTL1KDM4ECYP1A2
SCHEMBL5293777 0.76 LMNA (0.61) LMNANPSR1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0615855-B1 Recording sheets containing pyridinium and/or piperazinum compounds XEROX CORP (US) 1997-05-14 EP claimed
US-20230192614-A1 METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE CHENGDA PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192614-A1 METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE CHENGDA PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 US disclosed
US-10881653-B2 Tricyclic compounds and their use in the treatment of cancer THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-01-05 US disclosed
US-20200113889-A1 TRICYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2020-04-16 US disclosed
US-7488572-B2 Image formation method FUJIFILM CORPORATION (JP) 2009-02-10 US disclosed
US-7488572-B2 Image formation method FUJIFILM CORPORATION (JP) 2009-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192614-A1 METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE TALDO1, RPL22, RPS20 LMNA 533/4885NPSR1 1320/4885L3MBTL1 1388/4885
US-10881653-B2 Tricyclic compounds and their use in the treatment of cancer TP53, TOP2A, TK2 LMNA 714/4885NPSR1 1722/4885L3MBTL1 1302/4885
US-20200113889-A1 TRICYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER TP53, TOP2A, TK2 LMNA 714/4885NPSR1 1722/4885L3MBTL1 1302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.