Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628597 | 0.69 | — | — | |
| SCHEMBL277733 | 0.64 | — | — | |
| SCHEMBL1128286 | 0.62 | HPGD (0.35) | ALDH1A1 | |
| SCHEMBL503407 | 0.59 | KDM4E (0.32) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2045954 | 0.59 | — | — | |
| SCHEMBL6860201 | 0.59 | — | — | |
| SCHEMBL277548 | 0.59 | — | — | |
| SCHEMBL900852 | 0.58 | KDM4E (0.31) | KDM4EALDH1A1TDP1 | |
| SCHEMBL900796 | 0.58 | KDM4E (0.31) | KDM4EALDH1A1TDP1 | |
| SCHEMBL900846 | 0.58 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156782-A | Parasiticidal compounds | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| US-6069157-A | Parasiticidal compounds | PFIZER INC. (US) | 2000-05-30 | — | — | US | disclosed |