⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042356 | 0.59 | — | — | |
| SCHEMBL8085266 | 0.59 | KDM4E (0.32) | — | |
| SCHEMBL447176 | 0.59 | — | — | |
| SCHEMBL145124 | 0.54 | ALDH1A1 (0.52) | — | |
| SCHEMBL9567891 | 0.54 | — | — | |
| SCHEMBL2178457 | 0.53 | — | — | |
| SCHEMBL4835827 | 0.53 | — | — | |
| SCHEMBL13725004 | 0.51 | KDM4E (0.36) | — | |
| SCHEMBL900510 | 0.49 | KDM4E (0.41) | — | |
| SCHEMBL16289840 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812241-B2 | FOR PLANTS, HUMANS, VETERINARY MEDICINE | PFIZER INC. | 2004-11-02 | — | — | US | disclosed |
| US-20030130307-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2003-07-10 | — | — | US | disclosed |
| US-6525079-B2 | Antiparasitic compounds such as 4-(2,2-dibromocyclopropyl)-1-(2,6-dichloro-4-trifluoromethylphenyl)-1,2,3 -triazole | PFIZER INC. | 2003-02-25 | — | — | US | disclosed |
| EP-0846686-B1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | PFIZER LTD (GB) | 2002-01-09 | — | — | EP | disclosed |
| US-20010005725-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2001-06-28 | — | — | US | disclosed |
| US-6156782-A | Parasiticidal compounds | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| US-6083965-A | ANTIPARASITIC AGENTS | PFIZER INC (US) | 2000-07-04 | — | — | US | disclosed |
| US-6069157-A | Parasiticidal compounds | PFIZER INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0957094-A1 | 1-(2-Halogenaryl)azoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-17 | — | — | EP | disclosed |
| EP-0846686-A1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | Pfizer Limited (GB) | 1998-06-10 | — | — | EP | disclosed |