Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15703027 | 0.94 | NQO1 (0.52) | NQO1TDP1TSHRMAOBKDM4E | |
| SCHEMBL18358 | 0.89 | NQO1 (0.74) | NQO1TDP1TSHRMAOBKDM4E | |
| SCHEMBL3239122 | 0.89 | NQO1 (0.74) | NQO1TDP1TSHRKDM4EALDH1A1 | |
| SCHEMBL22015325 | 0.88 | NQO1 (0.45) | NQO1TDP1TSHRMAOBKDM4E | |
| SCHEMBL9804312 | 0.87 | NQO1 (0.70) | NQO1TDP1TSHRMAOBKDM4E | |
| Methyl Alcohol SCHEMBL27383198 | 0.85 | NQO1 (0.67) | NQO1TDP1TSHRMAOBKDM4E | |
| Bromoethane SCHEMBL9702775 | 0.85 | NQO1 (0.67) | NQO1TDP1TSHRMAOBKDM4E | |
| SCHEMBL19017946 | 0.83 | NQO1 (0.64) | NQO1TDP1TSHRKDM4EALDH1A1 | |
| SCHEMBL8943785 | 0.83 | LTA4H (0.65) | NQO1TDP1TSHRKDM4EALDH1A1 | |
| SCHEMBL6610130 | 0.83 | NQO1 (0.64) | NQO1TDP1TSHRMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918811-B1 | POLY(ARYLAMINES) AND FILMS THEREOF | DOW CHEMICAL CO (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0918811-A1 | POLY(ARYLAMINES) AND FILMS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998006773-A1 | POLY(ARYLAMINES) AND FILMS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |