SCHEMBL27520237

SCHEMBL27520237

CCNc1c(O)cccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.45
RECQL P46063 3/20 0.42
TSHR P16473 2/20 0.42
CYP3A4 P08684 2/20 0.42
CA2 P00918 5/20 0.39
CA1 P00915 3/20 0.39
LMNA P02545 3/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 2/20 0.39
EGFR P00533 2/20 0.39
FYN P06241 2/20 0.39
MMP9 P14780 2/20 0.39
ALOX15 P16050 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ADAMTS4 O75173 1/20 0.39
MMP2 P08253 1/20 0.39
MMP8 P22894 1/20 0.39
CA6 P23280 1/20 0.39
CDK2 P24941 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1953525 0.87 IDO1 (0.48) IDO1RECQLTSHRCYP3A4CA2
SCHEMBL4349574 0.87 TRPA1 (0.46) IDO1RECQLTSHRCYP3A4CA2
SCHEMBL10762942 0.79 GABRA1 (0.53) IDO1TSHRCA2CA1HPGD
SCHEMBL8085497 0.79 TYR (0.47) TSHRCYP3A4HSD17B10ALOX15TDP1
SCHEMBL15020230 0.78 GPR35 (0.51) TSHRALDH1A1TDP1MAPTNPC1
SCHEMBL28278777 0.75 CYP3A4 (0.47) IDO1RECQLTSHRCYP3A4CA2
SCHEMBL1954806 0.75 IDO1 (0.55) IDO1RECQLTSHRCYP3A4LMNA
SCHEMBL4624627 0.75 IDO1 (0.50) IDO1RECQLTSHRCYP3A4CA2
SCHEMBL1368372 0.73 IDO1 (0.59) IDO1RECQLTSHRCYP3A4CA2
SCHEMBL28851826 0.73 IDO1 (0.49) IDO1RECQLTSHRCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109851958-A A kind of high rigidity fluorubber and preparation method thereof 成都菁尚科技有限公司 2019-06-07 CN claimed
CN-109401144-A A kind of fluoro-rubber composite of high temperature and pressure contracting ratio and its application 江苏奥纳森弹性体技术研究院有限公司 2019-03-01 CN claimed
CN-105473121-B Hair decoloration is used or hair dyeing applies some make up 花王株式会社 2019-06-18 CN disclosed
CN-109789319-A Reduction of color loss from dyed materials by using amine salts of carboxylic acids 因诺斯佩克有限公司 2019-05-21 CN disclosed
CN-108430434-A Aerosol-type hair dye or hair bleach cosmetic 花王株式会社 2018-08-21 CN disclosed
CN-108366919-A Aerosol-type hair dye or hair bleach cosmetic 花王株式会社 2018-08-03 CN disclosed
CN-105473121-A Cosmetic product for hair decoloring or hair coloring KAO CORP 2016-04-06 CN disclosed
CN-102333515-B Hair colouring compositions BASF SE (DE) 2015-11-25 CN disclosed
CN-102405036-B Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2013-09-18 CN disclosed
CN-102405036-A Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2012-04-04 CN disclosed
CN-102405080-A Keratin dyeing compositions comprising radical scavengers and chelating agents and uses thereof PROCTER & GAMBLE 2012-04-04 CN disclosed
CN-1229100-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2005-11-30 CN disclosed
CN-1477947-A Primary intermediates for oxidative dyeing of hair P&G 2004-02-25 CN disclosed