Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559838 | 0.82 | CYP3A4 (0.43) | MAPTSMN1; SMN2L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL3787580 | 0.81 | HSD17B10 (0.52) | MAPTSMN1; SMN2ALDH1A1HSD17B10FOLH1 | |
| SCHEMBL1535068 | 0.80 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1HSD17B10FOLH1KMT2A | |
| SCHEMBL31212993 | 0.80 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1HSD17B10FOLH1KMT2A | |
| SCHEMBL9683905 | 0.80 | ALDH1A1 (0.55) | MAPTSMN1; SMN2L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL1250167 | 0.79 | BCAT2 (0.55) | MAPTL3MBTL1ALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8820705 | 0.78 | FOLH1 (0.52) | MAPTSMN1; SMN2L3MBTL1ALDH1A1FOLH1 | |
| SCHEMBL28019734 | 0.78 | ALDH1A1 (0.50) | MAPTL3MBTL1ALDH1A1HSD17B10FOLH1 | |
| SCHEMBL12998049 | 0.77 | ALDH1A1 (0.59) | MAPTSMN1; SMN2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL16173998 | 0.77 | FOLH1 (0.50) | MAPTSMN1; SMN2L3MBTL1ALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034211-A | β-sheet nucleating peptidomimetics | KELLY JEFFERY W (US) | 2000-03-07 | — | — | US | disclosed |