Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085529 | 0.78 | MAPT (0.47) | FOLH1DPP4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1868872 | 0.77 | DPP4 (0.68) | DPP4KMT2AADRA2CSMN1; SMN2TAAR1 | |
| SCHEMBL25171586 | 0.75 | FOLH1 (0.71) | FOLH1DPP4KMT2APTGER1PTGER4 | |
| Boric Acid SCHEMBL29044400 | 0.74 | DPP4 (0.55) | FOLH1DPP4KMT2AADRA2CPTGER1 | |
| Boric Acid SCHEMBL28704755 | 0.74 | DPP4 (0.59) | FOLH1DPP4KMT2AADRA2CPTGER1 | |
| SCHEMBL28181874 | 0.73 | FOLH1 (0.64) | FOLH1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL25264013 | 0.73 | FOLH1 (0.68) | FOLH1MAPT | |
| SCHEMBL25181448 | 0.73 | FOLH1 (0.68) | FOLH1DPP4KMT2APTGER1PTGER4 | |
| SCHEMBL7133141 | 0.72 | FOLH1 (0.50) | FOLH1DPP4KMT2APTGER1PTGER4 | |
| SCHEMBL28036728 | 0.72 | FOLH1 (0.71) | FOLH1DPP4KMT2APTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046547-A1 | β-SHEET NUCLEATING PEPTIDOMIMETICS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 1997-12-11 | — | — | WO | disclosed |