Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.66 |
| ▸ | RAB9A | P51151 | 14/20 | 0.66 |
| ▸ | GAA | P10253 | 11/20 | 0.66 |
| ▸ | NPC1 | O15118 | 9/20 | 0.66 |
| ▸ | GLA | P06280 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086614 | 0.96 | ALDH1A1 (0.67) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL8086607 | 0.94 | ALDH1A1 (0.67) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL7318575 | 0.81 | HRH3 (0.72) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL8078651 | 0.81 | RAB9A (0.74) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| Hydrochloric Acid SCHEMBL7314292 | 0.80 | HRH3 (0.71) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL8329392 | 0.80 | KDM4E (0.63) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL10753716 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL1692157 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL7681948 | 0.78 | HRH3 (0.75) | ALDH1A1KDM4ERAB9AGAANPC1 | |
| SCHEMBL23407642 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4ERAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103724-A | EXHIBIT MAINLY ANTIPSYCHOTIC EFFECTS, E.G., SCHIZOPHRENIA, ORGANIC MENTAL DISORDERS, AFFECTIVE DISORDERS, ANXIETY, PERSONALITY DISORDERS; NEUROLEPTIC ACTIVITIY; ATYPICAL ANTIPSYCHOTICS, COGNITION ACTIVATORS, ANTIDEPRESSANTS; | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2000-08-15 | — | — | US | disclosed |
| EP-0935599-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998018797-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1998-05-07 | — | — | WO | disclosed |