SCHEMBL8085752

SCHEMBL8085752

CC1CC(=O)Oc2ccc(C(C)(C)C)cc21

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.61
HPGD P15428 6/20 0.59
MAPT P10636 7/20 0.56
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
GLA P06280 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
CYP19A1 P11511 1/20 0.38
GAA P10253 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
RECQL P46063 1/20 0.36
ALDH2 P05091 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580157 0.79 ALDH1A1 (0.73) ALDH1A1HPGDMAPTGLAMEN1
SCHEMBL8080973 0.76 ALDH1A1 (0.40) ALDH1A1HPGDMAPTGLAMEN1
SCHEMBL7783242 0.76 ALDH1A1 (0.48) ALDH1A1HPGDMAPTCA12CA2
SCHEMBL28721813 0.74 TERT (0.41) ALDH1A1HPGDMAPTCA2MEN1
SCHEMBL28317314 0.74 ALDH1A1 (0.46) ALDH1A1HPGDMAPTGLAMEN1
SCHEMBL13714962 0.73 CYP19A1 (0.44) ALDH1A1HPGDMAPTCYP19A1HSD17B10
SCHEMBL18531165 0.73 CYP19A1 (0.44) ALDH1A1HPGDMAPTCYP19A1HSD17B10
SCHEMBL8080906 0.73 ALDH1A1 (0.47) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL14047016 0.73 ALDH1A1 (0.47) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL6125097 0.72 ALDH1A1 (0.45) ALDH1A1HPGDMAPTCA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036792-A1 Novel fragrance compound QUEST INTERNATIONAL B.V. (NL) 2000-09-20 EP disclosed