SCHEMBL8080906

SCHEMBL8080906

CC1CC(=O)Oc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.47
MAPT P10636 7/20 0.47
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
HPGD P15428 3/20 0.47
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.43
THRB P10828 1/20 0.43
ALDH2 P05091 1/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
RECQL P46063 1/20 0.40
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14047016 1.00 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL13183776 0.81 MEN1 (0.38) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL19821084 0.77 MAOA (0.50) MAPTMEN1KMT2AUSP2GAA
SCHEMBL15177926 0.77 MAOA (0.41) MAPTMEN1KMT2AUSP2MAOA
SCHEMBL15047842 0.77 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL7113968 0.77 MAOA (0.50) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL10531163 0.77 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL7360792 0.77 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL10247821 0.77 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL10192233 0.77 ALDH1A1 (0.48) ALDH1A1MAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11656549-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-05-23 US disclosed
US-11009790-B2 Photoacid generator and photoresist composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-18 US disclosed
US-10258602-B2 Macrocyclic ghrelin receptor modulators and methods of using the same OCERA THERAPEUTICS, INC. (US) 2019-04-16 US disclosed
US-9949949-B2 Macrocyclic ghrelin receptor modulators and methods of using the same OCERA THERAPEUTICS, INC. (US) 2018-04-24 US disclosed
US-20180039173-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-08 US disclosed
US-20180031967-A1 PHOTOACID GENERATOR AND PHOTORESIST COMPOSITION INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-01 US disclosed
US-20180031967-A1 PHOTOACID GENERATOR AND PHOTORESIST COMPOSITION INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-01 US disclosed
US-20170042858-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY 2017-02-16 US disclosed
US-20170042858-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY 2017-02-16 US disclosed
EP-2118080-B1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME OCERA THERAPEUTICS INC (US) 2016-08-31 EP disclosed
CN-102458394-A Treatment or prevention of proliferative conditions UNIV DUNDEE 2012-05-16 CN disclosed
WO-2011107608-A1 HETEROCYCLIC AMIDES AS ROCK INHIBITORS AMAKEM NV (BE) 2011-09-09 WO disclosed
WO-2008130464-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME TRANZYME PHARMA, INC. (US) 2008-10-30 WO disclosed
US-20080257188-A1 INK COMPOSITION, INKJET RECORDING METHOD, PRINTED MATERIAL, PRODUCTION METHOD OF A PLANOGRAPHIC PRINTNG PLATE AND PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080257188-A1 INK COMPOSITION, INKJET RECORDING METHOD, PRINTED MATERIAL, PRODUCTION METHOD OF A PLANOGRAPHIC PRINTNG PLATE AND PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080194672-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME TRANZYME PHARMA INC. 2008-08-14 US disclosed
US-20080194672-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME TRANZYME PHARMA INC. 2008-08-14 US disclosed
US-20080173215-A1 Cellulose Acylate Film, and Polarizing Plate and Liquid-Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080173215-A1 Cellulose Acylate Film, and Polarizing Plate and Liquid-Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
EP-1036792-A1 Novel fragrance compound QUEST INTERNATIONAL B.V. (NL) 2000-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10258602-B2 Macrocyclic ghrelin receptor modulators and methods of using the same GHSR, GHRHR, GIPR ALDH1A1 4297/4885MAPT 4766/4885MEN1 611/4885
US-20180031967-A1 PHOTOACID GENERATOR AND PHOTORESIST COMPOSITION INCLUDING THE SAME PAG1, CCNT1, NAT1 ALDH1A1 83/4885MAPT 2911/4885MEN1 1217/4885
US-20170042858-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME GHSR, GHRHR, GIPR ALDH1A1 4245/4885MAPT 4808/4885MEN1 493/4885
US-11009790-B2 Photoacid generator and photoresist composition including the same PAG1, CCNT1, NAT1 ALDH1A1 83/4885MAPT 2911/4885MEN1 1217/4885
US-20080194672-A1 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME GHSR, GHRHR, GIPR ALDH1A1 4297/4885MAPT 4766/4885MEN1 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.