Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621983 | 0.82 | PKM (0.69) | PKMTDP1MAPTKDM4EPOLB | |
| SCHEMBL30105934 | 0.82 | PKM (0.69) | PKMTDP1MAPTKDM4EPOLB | |
| SCHEMBL8091128 | 0.81 | CNR2 (0.53) | CNR2S1PR3PPARGPPARATDP1 | |
| SCHEMBL6799711 | 0.81 | MEN1 (0.40) | CNR2TDP1MAPTPLA2G4BKDM4E | |
| SCHEMBL5903146 | 0.81 | MEN1 (0.40) | CNR2TDP1MAPTPLA2G4BKDM4E | |
| SCHEMBL8085009 | 0.80 | CNR2 (0.52) | CNR2S1PR3PPARGPPARATDP1 | |
| SCHEMBL8085046 | 0.80 | CNR2 (0.52) | CNR2S1PR3PPARGPPARATDP1 | |
| SCHEMBL12777765 | 0.80 | PKM (0.43) | PKMCNR2S1PR3MAPTPLA2G4B | |
| SCHEMBL7822540 | 0.80 | CTSV (0.53) | PKMTDP1MAPTPOLBL3MBTL1 | |
| SCHEMBL5903298 | 0.80 | MEN1 (0.45) | CNR2TDP1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |