Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214627 | 0.90 | PTPN11 (0.54) | CNR2MAPTPTPN11S1PR3PLA2G4B | |
| SCHEMBL9446390 | 0.87 | CNR2 (0.47) | CNR2PTPN11S1PR3PLA2G4BPTPN1 | |
| SCHEMBL8085009 | 0.84 | CNR2 (0.52) | CNR2PPARAPPARGMAPTTDP1 | |
| SCHEMBL8085046 | 0.84 | CNR2 (0.52) | CNR2PPARAPPARGMAPTTDP1 | |
| SCHEMBL8089513 | 0.82 | CNR2 (0.50) | CNR2PPARAPPARGMAPTTDP1 | |
| SCHEMBL28886160 | 0.82 | CNR2 (0.43) | CNR2MAPTPTPN11S1PR3PTPN1 | |
| SCHEMBL8086102 | 0.81 | PKM (0.52) | CNR2PPARAPPARGMAPTTDP1 | |
| SCHEMBL2449812 | 0.81 | SMN1; SMN2 (0.53) | CNR2PPARAPPARGMAPTPTPN11 | |
| SCHEMBL28359092 | 0.81 | PTPN11 (0.57) | CNR2MAPTPTPN11S1PR3PLA2G4B | |
| SCHEMBL6770688 | 0.80 | LMNA (0.54) | CNR2PPARAPPARGMAPTPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |