Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.31 |
| ▸ | PPARG | P37231 | 7/20 | 0.31 |
| ▸ | PPARD | Q03181 | 7/20 | 0.31 |
| ▸ | PPARA | Q07869 | 7/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578768 | 0.82 | AKR1B1 (0.37) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL4384333 | 0.80 | TSHR (0.40) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL4389899 | 0.78 | TSHR (0.34) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL1302163 | 0.78 | AKR1B1 (0.36) | TSHRALDH1A1SLC22A6AKR1B1GPR84 | |
| SCHEMBL3675477 | 0.77 | GPR84 (0.41) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL3678894 | 0.77 | GPR84 (0.41) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL136592 | 0.76 | LMNA (0.42) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL4394670 | 0.75 | TSHR (0.39) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL4382366 | 0.75 | PRKCA (0.33) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL4383481 | 0.75 | TSHR (0.35) | TSHRALDH1A1LMNASLC22A6AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010595-A | DISPOSABLE PRODUCTS | EASTMAN CHEMICAL COMPANY (US) | 2000-01-04 | — | — | US | disclosed |