Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096631 | 0.94 | LMNA (0.45) | ALDH1A1KDM4ELMNAPOLBSIGMAR1 | |
| Diethylamine SCHEMBL11106466 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBHTR2A | |
| Phosphonic Acid SCHEMBL9264939 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8095438 | 0.90 | LMNA (0.52) | ALDH1A1KDM4ELMNASIGMAR1HTR2A | |
| SCHEMBL10778745 | 0.87 | KDM4E (0.47) | ALDH1A1KDM4ELMNAPOLBSIGMAR1 | |
| SCHEMBL8101789 | 0.83 | LMNA (0.52) | LMNAPOLBHTR2AHRH1AOC3 | |
| SCHEMBL689624 | 0.81 | MAPT (0.37) | ALDH1A1KDM4ELMNAMAPTMAPK1 | |
| SCHEMBL2164780 | 0.81 | KDM4E (0.33) | ALDH1A1KDM4E | |
| SCHEMBL13122615 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBASAH1 | |
| SCHEMBL395463 | 0.81 | ESR1 (0.48) | ALDH1A1KDM4ELMNAOPRM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |