Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086502 | 0.94 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4ESIGMAR1HTR2A | |
| SCHEMBL8095438 | 0.88 | LMNA (0.52) | LMNAALDH1A1KDM4ESIGMAR1HTR2A | |
| Phosphonic Acid SCHEMBL9264939 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4EASAH1NAAA | |
| Diethylamine SCHEMBL11106466 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EHTR2AASAH1 | |
| SCHEMBL10778745 | 0.82 | KDM4E (0.47) | LMNAALDH1A1KDM4ESIGMAR1POLB | |
| SCHEMBL8101789 | 0.81 | LMNA (0.52) | LMNAHTR2APOLB | |
| SCHEMBL9099644 | 0.78 | LMNA (0.47) | LMNAALDH1A1KDM4ESIGMAR1HTR2A | |
| SCHEMBL8095531 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4ESIGMAR1HTR2AASAH1 | |
| SCHEMBL27692950 | 0.78 | DPP4 (0.45) | SIGMAR1HTR2AOPRM1OPRD1OPRK1 | |
| SCHEMBL28218362 | 0.78 | LMNA (0.61) | LMNAALDH1A1KDM4EASAH1CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |