Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568313 | 1.00 | CHRNA7 (0.49) | CHRNA7GAAMEN1KMT2AMTNR1A | |
| SCHEMBL8568310 | 1.00 | CHRNA7 (0.49) | CHRNA7GAAMEN1KMT2AMTNR1A | |
| SCHEMBL8086570 | 0.86 | MTNR1A (0.50) | GAAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL9036114 | 0.86 | MTNR1A (0.50) | GAAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL29073380 | 0.82 | MTNR1A (0.49) | GAAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8562147 | 0.82 | MTNR1A (0.56) | GAAKMT2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562145 | 0.82 | MTNR1A (0.56) | GAAKMT2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562150 | 0.82 | MTNR1A (0.56) | GAAKMT2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL9035962 | 0.81 | MTNR1A (0.49) | GAAKMT2AMTNR1AMTNR1BEPHX2 | |
| SCHEMBL9430690 | 0.80 | CHRNA7 (0.53) | CHRNA7GAAMEN1KMT2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |