Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086570 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL9036114 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562147 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562145 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562150 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568310 | 0.81 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568312 | 0.81 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL17049225 | 0.81 | EPHX2 (0.54) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568313 | 0.81 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL29073380 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |