Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930567 | 0.86 | KDM4E (0.72) | KDM4EHPGDLMNAALDH1A1RXFP1 | |
| SCHEMBL8081787 | 0.79 | CNR1 (0.48) | KDM4EHPGDLMNAALDH1A1KMT2A | |
| SCHEMBL8086591 | 0.76 | CNR2 (0.56) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL24221933 | 0.70 | KMT2A (0.46) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28050524 | 0.70 | MEN1 (0.56) | KDM4EHPGDLMNAALDH1A1KMT2A | |
| SCHEMBL22925970 | 0.70 | LMNA (0.57) | KDM4EHPGDLMNAALDH1A1RXFP1 | |
| SCHEMBL8071307 | 0.69 | MAPKAPK2 (0.46) | LMNAALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8082051 | 0.69 | HCAR3 (0.49) | KDM4EALDH1A1KMT2AMEN1P4HTM | |
| SCHEMBL12978173 | 0.68 | KDM4E (0.71) | KDM4EHPGDLMNAALDH1A1RXFP1 | |
| SCHEMBL29425707 | 0.68 | LMNA (1.00) | KDM4EHPGDLMNAALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |