Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086591 | 0.90 | CNR2 (0.56) | ALDH1A1MEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL4252309 | 0.86 | P4HTM (0.61) | CNR1ALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL13930597 | 0.85 | P4HTM (0.60) | CNR1ALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL4249417 | 0.83 | P4HTM (0.61) | CNR1ALDH1A1MEN1KMT2AKCNQ3 | |
| SCHEMBL8086323 | 0.79 | KDM4E (0.54) | ALDH1A1MEN1KMT2ANPSR1NPC1 | |
| SCHEMBL4919397 | 0.79 | CNR1 (0.62) | CNR1ALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL3952279 | 0.77 | DGAT1 (0.52) | CNR1ALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL3679282 | 0.76 | P4HTM (0.58) | ALDH1A1RAB9ALMNAP4HTMDGAT1 | |
| SCHEMBL4247530 | 0.76 | MAPT (0.69) | ALDH1A1KCNQ3KCNQ2NPC1RAB9A | |
| SCHEMBL3680529 | 0.76 | RAB9A (0.69) | ALDH1A1MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |