SCHEMBL8086831

SCHEMBL8086831

CCc1c(Cl)cc(NC(=O)COc2ccc(C)cc2C(C)(C)CC)c(O)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.42
TP53 P04637 3/20 0.41
SMN1; SMN2 Q16637 5/20 0.39
ALDH1A1 P00352 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 2/20 0.39
MAPT P10636 5/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPC1 O15118 5/20 0.38
ATM Q13315 2/20 0.38
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
RAB9A P51151 4/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075464 0.90 SMN1; SMN2 (0.51) HTTSMN1; SMN2ALDH1A1NPSR1MEN1
SCHEMBL8087137 0.90 HTT (0.43) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL8088633 0.82 TSHR (0.33) TP53ALDH1A1NPSR1MEN1KMT2A
SCHEMBL8083289 0.82 SMN1; SMN2 (0.52) HTTSMN1; SMN2ALDH1A1NPSR1MEN1
SCHEMBL10763854 0.77 SMN1; SMN2 (0.51) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL11344675 0.75 KMT2A (0.56) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL11414371 0.74 MAPK1 (0.48) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL3429177 0.73 KMT2A (0.39) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL10713506 0.73 MAPK1 (0.48) HTTTP53SMN1; SMN2ALDH1A1NPSR1
SCHEMBL8083783 0.72 TSHR (0.34) ALDH1A1NPSR1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed