SCHEMBL8087137

SCHEMBL8087137

CCC(C)(C)c1cc(C)ccc1OCC(=O)Nc1cc(Cl)c(C)c(Cl)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.43
TP53 P04637 3/20 0.42
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPK1 P28482 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPC1 O15118 5/20 0.39
ATM Q13315 2/20 0.39
RAB9A P51151 4/20 0.39
POLB P06746 2/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 5/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083289 0.91 SMN1; SMN2 (0.52) HTTALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL8086831 0.90 HTT (0.42) HTTTP53ALDH1A1SMN1; SMN2NPSR1
SCHEMBL8083783 0.82 TSHR (0.34) ALDH1A1NPSR1MEN1KMT2APOLB
SCHEMBL8656152 0.81 MAPK1 (0.44) HTTTP53ALDH1A1SMN1; SMN2NPSR1
SCHEMBL8075464 0.80 SMN1; SMN2 (0.51) HTTALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL11414371 0.79 MAPK1 (0.48) HTTTP53ALDH1A1SMN1; SMN2NPSR1
SCHEMBL10713506 0.78 MAPK1 (0.48) HTTTP53ALDH1A1SMN1; SMN2NPSR1
SCHEMBL11155394 0.77 MAPK1 (0.54) HTTALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL11344675 0.76 KMT2A (0.56) HTTTP53ALDH1A1SMN1; SMN2NPSR1
SCHEMBL11475945 0.76 NPSR1 (0.39) HTTALDH1A1SMN1; SMN2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed