Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287071 | 0.94 | ALDH1A1 (0.42) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL9287554 | 0.89 | GSK3B (0.41) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL9282960 | 0.88 | GSK3B (0.43) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL8085817 | 0.87 | MEN1 (0.56) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL9266139 | 0.85 | MEN1 (0.54) | MEN1PGRKMT2AALDH1A1KDM4E | |
| SCHEMBL9269029 | 0.84 | MEN1 (0.46) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL9267786 | 0.84 | GSK3B (0.41) | GSK3BALDH1A1KDM4EGAAHIF1A | |
| SCHEMBL10672221 | 0.82 | MEN1 (0.56) | GSK3BMEN1PGRKMT2AALDH1A1 | |
| SCHEMBL10679151 | 0.79 | KMT2A (0.60) | MEN1PGRKMT2AALDH1A1KDM4E | |
| SCHEMBL9267602 | 0.79 | MAPT (0.41) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048296-A1 | DRUGS AUGMENTING NKT CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | claimed |
| CN-1284878-A | Drugs augmenting NKT cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-02-21 | — | — | CN | disclosed |
| EP-1048296-A1 | DRUGS AUGMENTING NKT CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |