Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287071 | 0.81 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9266139 | 0.81 | MEN1 (0.54) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8086963 | 0.79 | GSK3B (0.43) | SMN1; SMN2ALDH1A1KDM4EHTTHPGD | |
| SCHEMBL9268657 | 0.77 | KCNH2 (0.41) | ALDH1A1 | |
| SCHEMBL10679151 | 0.77 | KMT2A (0.60) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL10672221 | 0.71 | MEN1 (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9269052 | 0.71 | HIF1A (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10676615 | 0.70 | MEN1 (0.71) | MAPTSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9282960 | 0.69 | GSK3B (0.43) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL9287554 | 0.68 | GSK3B (0.41) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |