Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086963 | 0.88 | GSK3B (0.43) | GSK3BLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL9287071 | 0.84 | ALDH1A1 (0.42) | GSK3BSMN1; SMN2ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL9287554 | 0.84 | GSK3B (0.41) | GSK3BLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL8085817 | 0.82 | MEN1 (0.56) | GSK3BALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL9269029 | 0.79 | MEN1 (0.46) | GSK3BALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL9266139 | 0.76 | MEN1 (0.54) | HTTSMN1; SMN2NPSR1ALDH1A1HIF1A | |
| SCHEMBL9267786 | 0.75 | GSK3B (0.41) | GSK3BALDH1A1HIF1AKDM4EGAA | |
| SCHEMBL9284056 | 0.75 | GSK3B (0.46) | GSK3BALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL9279359 | 0.74 | MEN1 (0.56) | GSK3BALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL10672221 | 0.73 | MEN1 (0.56) | GSK3BSMN1; SMN2ALDH1A1HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |