Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 14/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087172 | 0.88 | ELOVL6 (0.54) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3037679 | 0.83 | ELOVL6 (0.62) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| Hydrochloric Acid SCHEMBL3033669 | 0.82 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3034041 | 0.81 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3036325 | 0.81 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3044483 | 0.79 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL17273553 | 0.79 | CYP46A1 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL3041683 | 0.79 | ELOVL6 (0.58) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL7704788 | 0.79 | CYP46A1 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 | |
| SCHEMBL13908047 | 0.78 | ELOVL6 (0.60) | ELOVL6CYP46A1PGRNR1I2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210880-B1 | Benzoxazinone derivatives | MSD KK (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8314094-B2 | Benzoxazinone derivative | MSD K.K (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2010-08-19 | — | — | US | disclosed |
| EP-2210880-A1 | BENZOXAZINONE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | HAX1, CYP4X1, CYP19A1 | ELOVL6 3630/4885CYP46A1 114/4885PGR 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.