SCHEMBL8087232

SCHEMBL8087232

O=C(CC(CCc1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.56
DPP4 P27487 1/20 0.55
L3MBTL1 Q9Y468 3/20 0.53
NPC1 O15118 1/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
F10 P00742 2/20 0.49
F2 P00734 1/20 0.49
TSHR P16473 1/20 0.49
NPSR1 Q6W5P4 2/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28380583 0.84 F2 (0.52) DPP4F10F2TSHRACP3
SCHEMBL9066674 0.84 ATM (0.74) ATML3MBTL1NPC1TDP1TSHR
SCHEMBL28529442 0.83 ATM (0.59) ATML3MBTL1NPC1TDP1TSHR
SCHEMBL10033918 0.83 ATM (0.59) ATML3MBTL1TDP1TSHRNPSR1
SCHEMBL11699823 0.83 TDP1 (0.63) DPP4L3MBTL1NPC1CASP3RAB9A
SCHEMBL7330613 0.82 F10 (0.52) DPP4L3MBTL1NPC1RAB9AF10
SCHEMBL2363356 0.81 ALDH1A1 (0.52) F10F2TSHRHPGDALDH1A1
SCHEMBL4560570 0.81 F2 (0.53) F10F2NPSR1ALDH1A1SMN1; SMN2
SCHEMBL12001995 0.81 ATM (0.62) ATML3MBTL1NPC1TDP1TSHR
SCHEMBL6291574 0.80 F10 (0.43) DPP4F10F2HPGDACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000026336-A PRODUCTION OF STYRENE TRIMER SUMIKA CHEMICAL ANALYSIS SERVICE LTD 2000-01-25 JP disclosed