Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260887 | 0.93 | CTSB (0.65) | CTSBLTA4HANPEPRNPEPDNPEP | |
| SCHEMBL3487670 | 0.93 | CTSB (0.65) | CTSBLTA4HANPEPRNPEPDNPEP | |
| SCHEMBL30371890 | 0.87 | CTSB (0.58) | CTSBLTA4H | |
| SCHEMBL6248305 | 0.84 | CTSB (0.55) | CTSBSMN1; SMN2CTSD | |
| SCHEMBL7361635 | 0.84 | CTSB (0.59) | CTSBSMN1; SMN2 | |
| SCHEMBL20204722 | 0.84 | CTSB (0.62) | CTSBSMN1; SMN2 | |
| SCHEMBL10790323 | 0.83 | BACE1 (0.60) | CTSDLTA4HBACE1 | |
| SCHEMBL23463561 | 0.83 | CTSB (0.58) | CTSBLTA4HANPEPRNPEPDNPEP | |
| SCHEMBL7323888 | 0.82 | FCER2 (0.58) | CTSDBACE1 | |
| SCHEMBL29601744 | 0.81 | BACE1 (0.60) | CTSBCTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039925-A1 | ALTERATION OF THE CELL CYCLE IN VIVO, AND PARTICULARLY FOR INDUCING APOPTOSIS OF TUMOR CELLS | ALFACELL CORPORATION (US) | 2000-10-04 | — | — | EP | claimed |
| WO-2000007619-A1 | ALTERATION OF THE CELL CYCLE IN VIVO, AND PARTICULARLY FOR INDUCING APOPTOSIS OF TUMOR CELLS | ALFACELL CORPORATION (US) | 2000-02-17 | — | — | WO | claimed |