Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252846 | 0.79 | — | — | |
| SCHEMBL17322700 | 0.71 | GABRA1 (0.31) | — | |
| SCHEMBL7319565 | 0.69 | SLC1A3 (0.32) | SLC7A5 | |
| SCHEMBL6278994 | 0.66 | ABHD6 (0.33) | — | |
| SCHEMBL12563237 | 0.66 | SLC7A5 (0.42) | SLC7A5 | |
| SCHEMBL6131295 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL31308990 | 0.65 | TSHR (0.31) | — | |
| SCHEMBL28085799 | 0.64 | LMNA (0.36) | SLC7A5 | |
| SCHEMBL12869032 | 0.63 | TSHR (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL3252844 | 0.63 | SLC7A5 (0.34) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037363-A | Diastereomeric pure trifluoromethyl ketone peptide derivatives as inhibitors of human leukocyte elastase | ZENECA LIMITED (GB) | 2000-03-14 | — | — | US | disclosed |
| US-5907043-A | Diastereomeric pure trifluoromethyl ketone peptide derivatives as inhibitors of human leukocyte elastase | ZENECA LIMITED (GB) | 1999-05-25 | — | — | US | disclosed |
| US-5739157-A | Diastereomeric pure trifluoromethyl ketone peptide derivatives as inhibitors of human leukocyte elastase | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |