SCHEMBL8087586

SCHEMBL8087586

O=C(O)c1ccc(B2OCCNCCO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
TP53 P04637 1/20 0.41
OPRD1 P41143 2/20 0.39
SRD5A2 P31213 3/20 0.38
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA4 P22748 2/20 0.36
CA9 Q16790 2/20 0.36
MAPT P10636 1/20 0.36
CA3 P07451 1/20 0.36
TYR P14679 1/20 0.36
DRD1 P21728 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4465763 0.87 TSHR (0.50) TSHRTP53SRD5A2CA1CA2
SCHEMBL2944623 0.84 TSHR (0.46) TSHRTP53SRD5A2CA1CA2
SCHEMBL31336278 0.77 HTR2C (0.34)
Terephthalic Acid SCHEMBL31728763 0.77 TSHR (0.52) TSHRTP53OPRD1SRD5A2CA1
SCHEMBL8083423 0.72 TSHR (0.41) TSHRTP53SRD5A2CA1CA2
Paraben SCHEMBL5893390 0.71 CA2 (0.59) TSHRTP53OPRD1SRD5A2CA1
Terephthalic Acid SCHEMBL31729036 0.71 TSHR (0.60) TSHRTP53OPRD1SRD5A2CA1
Benzoic Acid SCHEMBL7026585 0.71 TSHR (0.56) TSHRTP53OPRD1SRD5A2MAPT
Terephthalic Acid SCHEMBL30526425 0.71 TSHR (0.48) TSHRTP53OPRD1SRD5A2CA1
4-Methylbenzoic Acid SCHEMBL28030084 0.70 ALDH1A1 (0.61) TSHRTP53SRD5A2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1046640-A2 Process for preparing substituted phenyl boronic acids Clariant GmbH (DE) 2000-10-25 EP disclosed