SCHEMBL4465763

SCHEMBL4465763

O=C(O)c1ccc(B2OCCO2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
SRD5A2 P31213 4/20 0.44
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA12 O43570 2/20 0.43
CA4 P22748 2/20 0.43
CA9 Q16790 2/20 0.43
CA3 P07451 1/20 0.43
TYR P14679 1/20 0.43
DRD1 P21728 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
HPGD P15428 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 1/20 0.41
TPMT P51580 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2944623 0.92 TSHR (0.46) TSHRTP53SRD5A2CA1CA2
SCHEMBL8087586 0.87 TSHR (0.41) TSHRTP53SRD5A2CA1CA2
SCHEMBL8083423 0.80 TSHR (0.41) TSHRTP53SRD5A2CA1CA2
SCHEMBL4374187 0.79 LPL (0.30)
SCHEMBL29033937 0.77 TSHR (0.52) TSHRTP53SRD5A2CA1CA2
SCHEMBL12425772 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL18256762 0.75 SMN1; SMN2 (0.41) CA1CA2HPGDALDH1A1SMN1; SMN2
Terephthalic Acid SCHEMBL27534277 0.74 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL2049859 0.74 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL8160118 0.74 TSHR (0.92) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542939-A1 OLIGOMERIC DISPERSANT Construction Research & Technology GmbH (DE) 2005-06-22 EP claimed
US-6861459-B2 Making a dry cast article with hydraulic cement, water, coarse particles and a polymeric flow control agents CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-03-01 US claimed
WO-2004024647-A1 OLIGOMERIC DISPERSANT CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-03-25 WO claimed
US-20030181579-A1 Oligomeric dispersant CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2003-09-25 US claimed
US-20030144385-A1 Oligomeric dispersant CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2003-07-31 US claimed
US-6451881-B1 Oligomeric dispersant MBT HOLDINGAG (CH) 2002-09-17 US claimed
US-6133347-A CEMENT AND A DISPERSANT COMPRISING THE REACTION PRODUCT OF A WATER SOLUBLE NONIONIC POLYMER NONADSORBING TO CEMENT PARTICLES, SUCH AS POLYOXYALKYLENE GLYCOLS, AND SPECIFIED FUNCTIONAL MOIETY THAT ADSORB ONTO A PARTICLE MBT HOLDING AG (CH) 2000-10-17 US claimed
US-8747870-B2 Polymeric compositions and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2014-06-10 US disclosed
US-8747870-B2 Polymeric compositions and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2014-06-10 US disclosed
US-20130164249-A1 COMPOSITIONS AND METHODS FOR INHIBITING VIRAL AND BACTERIAL ACTIVITY KISER PATRICK F (US) 2013-06-27 US disclosed
US-20130164249-A1 COMPOSITIONS AND METHODS FOR INHIBITING VIRAL AND BACTERIAL ACTIVITY KISER PATRICK F (US) 2013-06-27 US disclosed
US-20130129797-A1 POLYMERIC COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-05-23 US disclosed
US-20130129797-A1 POLYMERIC COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-05-23 US disclosed
US-6492461-B1 REACTION PRODUCT OF TWO OR THREE MOIETIES. THE FIRST MOIETY (A) IS A NONPOLYMERIC, FUNCTIONAL MOIETY THAT CAN ADSORB ONTO A PARTICLE. THE SECOND REQUIRED MOIETY (C) IS A LINEAR OR BRANCHED WATER SOLUBLE, NONIONIC POLYMER THAT IS CAPABLE OF MBT HOLDING AG (CH) 2002-12-10 US disclosed
US-6451881-B1 Oligomeric dispersant MBT HOLDINGAG (CH) 2002-09-17 US disclosed
EP-1203046-A1 OLIGOMERIC DISPERSANT MBT HOLDING AG (CH) 2002-05-08 EP disclosed
US-6197967-B1 CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION CLARIANT GMBH (DE) 2001-03-06 US disclosed
WO-2001004185-A1 OLIGOMERIC DISPERSANT MBT HOLDING AG (CH) 2001-01-18 WO disclosed
EP-1046640-A2 Process for preparing substituted phenyl boronic acids Clariant GmbH (DE) 2000-10-25 EP disclosed
US-6133347-A CEMENT AND A DISPERSANT COMPRISING THE REACTION PRODUCT OF A WATER SOLUBLE NONIONIC POLYMER NONADSORBING TO CEMENT PARTICLES, SUCH AS POLYOXYALKYLENE GLYCOLS, AND SPECIFIED FUNCTIONAL MOIETY THAT ADSORB ONTO A PARTICLE MBT HOLDING AG (CH) 2000-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130164249-A1 COMPOSITIONS AND METHODS FOR INHIBITING VIRAL AND BACTERIAL ACTIVITY BLVRB, RNASE1, BPGM TSHR 4049/4885TP53 1107/4885SRD5A2 4748/4885
US-20130129797-A1 POLYMERIC COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF PCBP1, PARG, PHYKPL TSHR 4424/4885TP53 2465/4885SRD5A2 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.