Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 12/20 | 1.00 |
| ▸ | CA12 | O43570 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 7/20 | 0.70 |
| ▸ | CA2 | P00918 | 4/20 | 0.70 |
| ▸ | RORC | P51449 | 1/20 | 0.66 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.62 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.62 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.62 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.62 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364474 | 0.85 | CA9 (0.74) | CA9CA12ALDH1A1CA1CA2 | |
| SCHEMBL6825144 | 0.84 | CA9 (0.72) | CA9CA12ALDH1A1CA1CA2 | |
| SCHEMBL5267617 | 0.83 | CA9 (0.69) | CA9CA12ALDH1A1CA1CA2 | |
| SCHEMBL27268243 | 0.80 | CA9 (0.77) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL28266787 | 0.80 | RORC (1.00) | CA9CA12ALDH1A1CA2RORC | |
| SCHEMBL8087744 | 0.80 | CXCR3 (0.71) | CA9CA12ALDH1A1CA1CA2 | |
| SCHEMBL28266792 | 0.80 | RORC (0.83) | CA9CA12ALDH1A1CA2RORC | |
| SCHEMBL12863861 | 0.79 | CXCR3 (0.80) | CA9CA12ALDH1A1RORCCXCR3 | |
| SCHEMBL4016252 | 0.79 | CA9 (0.78) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL21975646 | 0.79 | CA9 (1.00) | CA9CA12CA1CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047670-A1 | AMINOSULPHONYLBENZAMIDE DERIVATIVES AS MODULATORS OF THE ACTIVITY OF NEURONAL CALCIUM CHANNELS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036398-A1 | AMINOSULPHONYLBENZAMIDE DERIVATIVES AS MODULATORS OF THE ACTIVITY OF NEURONAL CALCIUM CHANNELS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-22 | — | — | WO | disclosed |