Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 7/20 | 0.37 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824936 | 0.90 | PRSS1 (0.38) | APPCYP2D6MAPTRAB9ACYP2C19 | |
| SCHEMBL6560645 | 0.83 | APP (0.39) | APPCYP2D6MAPTRAB9ACYP2C19 | |
| SCHEMBL9816503 | 0.83 | CA1 (0.39) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL3474221 | 0.83 | CA2 (0.33) | MAPTMAPK1CA1CA2CA9 | |
| SCHEMBL15044746 | 0.83 | MAPT (0.53) | MAPTRAB9AMAPK1CA1CA2 | |
| SCHEMBL8431544 | 0.82 | ALDH1A1 (0.47) | MAPTMAPK1CA1CA2CA9 | |
| SCHEMBL4821832 | 0.82 | RECQL (0.50) | APPCYP2D6MAPTRAB9ACYP2C19 | |
| SCHEMBL9816419 | 0.81 | TYMS (0.39) | CA1CA2CA9CA12PKM | |
| SCHEMBL8087721 | 0.81 | DDX3X (0.44) | CYP2D6MAPTCYP2C19CYP3A4CA1 | |
| SCHEMBL4825163 | 0.80 | CYP2D6 (0.59) | APPCYP2D6MAPTRAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717084-B1 | Water soluble fibre reactive anthraquinone compounds | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2000-11-22 | — | — | EP | disclosed |
| US-5744622-A | water-soluble, fiber-reactive anthraquinone compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0717084-A1 | Water soluble fibre reactive anthraquinone compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-19 | — | — | EP | disclosed |