Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083654 | 0.88 | LMNA (0.68) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL9128299 | 0.84 | LMNA (0.71) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL9037446 | 0.83 | LMNA (0.76) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL19911300 | 0.83 | LMNA (1.00) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL9123166 | 0.83 | LMNA (0.69) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL9128979 | 0.82 | LMNA (0.73) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL13668113 | 0.80 | LMNA (0.66) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL15779866 | 0.80 | LMNA (0.81) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL4185454 | 0.79 | LMNA (0.64) | LMNAMAPTTP53HTTMEN1 | |
| SCHEMBL30199049 | 0.78 | LMNA (0.68) | LMNAMAPTTP53HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |