Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 3/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | MERTK | Q12866 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619914 | 0.95 | HRH4 (0.55) | DNM2HRH4MERTKTLR8KCNH3 | |
| SCHEMBL16139311 | 0.88 | DNM2 (0.46) | DNM2HRH4MERTKTLR8KMT2A | |
| SCHEMBL1401613 | 0.85 | DNM2 (0.78) | DNM2HRH4MERTKTLR8KCNH3 | |
| SCHEMBL28248600 | 0.81 | DNM2 (0.57) | DNM2HRH4MERTKTLR8KCNH3 | |
| SCHEMBL2763279 | 0.81 | NUDT1 (0.53) | DNM2MERTKKCNH3MAPTHTT | |
| SCHEMBL14907961 | 0.81 | STK17A (0.57) | DNM2HRH4STK17A | |
| SCHEMBL1519442 | 0.80 | LMNA (0.47) | DNM2HRH4 | |
| SCHEMBL8088117 | 0.80 | DNM2 (0.56) | DNM2HRH4MERTKTLR8KCNH3 | |
| SCHEMBL2574817 | 0.80 | DNM2 (0.56) | DNM2HRH4MERTKTLR8KCNH3 | |
| SCHEMBL19477219 | 0.79 | DNM2 (0.71) | DNM2HRH4MERTKTLR8MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598182-B2 | Insecticidal pyrimidinyl aryl hyrdrazones | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | claimed |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-12-29 | — | — | US | claimed |
| EP-2197853-B1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-11-09 | — | — | EP | claimed |
| EP-2197853-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | Dow AgroSciences LLC (US) | 2010-06-23 | — | — | EP | claimed |
| WO-2009048751-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | claimed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | DNM2 297/4885HRH4 30/4885MERTK 2678/4885 |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | DNM2 297/4885HRH4 30/4885MERTK 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.